Invivo Anti-Mouse CD22 Recombinant mAb
SKU: 10959841646

Invivo Anti-Mouse CD22 Recombinant mAb

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Description

Invivo Anti-Mouse CD22 Recombinant mAbProduct Specification Host Mouse Antigen CD22 Synonyms B cell receptor CD22; B lymphocyte cell adhesion molecule (BL CAM); Sialic acid binding Ig like lectin 2 (Siglec 2); T cell surface antigen Leu 14; Lyb 8; Siglec2; Cd22 Location Cell membrane Accession P35329 Clone Number S 3259 Antibody Type Mouse mAb Application FCM, in vivo B cell depletion in combination with anti CD19 and anti rat Light Chain Reactivity Ms Positive Sample BALB c mouse

Product Specification


Host Mouse
Antigen CD22
Synonyms B-cell receptor CD22; B-lymphocyte cell adhesion molecule (BL-CAM); Sialic acid-binding Ig-like lectin 2 (Siglec-2); T-cell surface antigen Leu-14; Lyb-8; Siglec2; Cd22
Location Cell membrane
Accession P35329
Clone Number S-3259
Antibody Type Mouse mAb
Application FCM, in vivo B cell depletion in combination with anti-CD19 and anti-rat κ Light Chain
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 5 mg/ml
Purity >95%(Determined by SDS-PAGE)
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.

Dilution


application dilution species
FCM 1:500 Ms

Background

CD22, also known as cluster of differentiation 22, is a 140 kDa type I transmembrane glycoprotein and a member of the Siglec (sialic acid-binding immunoglobulin-like lectin) family. It is predominantly expressed on the surface of mature B cells and to a lesser extent on some immature B cells. The extracellular domain of CD22 consists of seven immunoglobulin-like domains, while its cytoplasmic tail contains conserved tyrosine motifs, including immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which play a crucial role in inhibiting B cell receptor (BCR) signaling. CD22 functions as a negative regulator of B cell activation, helping to prevent overactivation of the immune system and the development of autoimmune diseases. Additionally, it is involved in B cell trafficking and maintaining peripheral B cell tolerance. CD22's interaction with sialic acid-containing molecules on various cell types allows it to modulate B cell responses and maintain immune homeostasis.

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SKU: 10959841646

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4.5 ★★★★★
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B
Bunny
Louisville, US
★★★★★ 5
Soft and comfy
Color: Green, Size: Twin, Color: Green, Size: Twin
This mattress pad is much thicker and fluffier than the one I had before. With I took it out of the package, it was vacuum sealed with a note saying to leave it out in the sun for 48-72 hours or fluff it up with a hair dryer. I put it in the dryer on medium heat, which worked nicely. The pockets are really deep on this mattress pad and it fits snug. You don’t really see the shape with a sheet on top. It feels comfortable laying on top of it. It doesn’t flatten much when I’m laying down, but I imagine over time it will lose fluffiness. Overall it’s comfortable and breathable.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026
E
Verified Purchase
EW
Lowell, US
★★★★★ 2
Good for already soft mattresses, 1in thickness.
Color: Dark Grey, Size: Queen
If your mattress is already soft, it will help. It's less than 1in thick after tumbling for 40 minutes. It did fit my queen bed and felt somewhat soft when laying down but it didn't help much as far as comfort. Quality wise it looks good, not cheap and while my sleep quality wasn't improved, it might help someone with a better mattress than mine.
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Reviewed in the United States on June 1, 2026
F
F&S
Port Orchard, US
★★★★★ 5
Must have for mattress comfort and protection
Color: Green, Size: Twin, Color: Green, Size: Twin
I ordered the BDEUS Twin mattress topper for a temporary mattress. The topper definitely improves comfort and regulates temperature much better than just the mattress and sheets. The cover fits deep mattress easily fitting over my 13” mattress and could easily fit a much deeper bed. The padding is thick enough to provide some additional support. This model also has a thin sheet of waterproof material to help protect your mattress against spills or liquid damage. This layer is cover by the pillow top and does not seem to make much if any noticeable noise. Overall this is a high quality cover and mattress protector in one. At <$45 at the time of this review it provides an incredible value.
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Reviewed in the United States on May 28, 2026
M
max haney
West Palm Beach, US
★★★★★ 5
Topper
Color: Green, Size: Twin
I recently purchased the BDEUS Twin Mattress Topper Viscose Derived from Bamboo, and I am thoroughly impressed with my experience. The comfort level is absolutely a 5 out of 5. The viscose bamboo material feels soft and plush, making my bed significantly more comfortable to sleep on. I wake up feeling well-rested and supported, which has been a noticeable improvement from before. Here are some of the main pros and cons: Pros: Incredible comfort and softness, high-quality materials, fits the twin mattress perfectly, and helps with temperature regulation throughout the night. Cons: Name Overall, I give the BDEUS Twin Mattress Topper a solid 5 out of 5 stars. It has completely transformed my sleeping experience, and I would highly recommend it to anyone looking to enhance the comfort of their bed.
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Reviewed in the United States on May 24, 2026
B
Book fanatic
New York, US
★★★★★ 5
Adds comfort and support
Color: Green, Size: Twin
I’ve been using this bamboo mattress topper for a couple of weeks now, and it completely changed the feel of my bed. My mattress was starting to feel too firm and uncomfortable, especially on my lower back and shoulders, but this topper added the perfect amount of cushioning without making the bed feel overly soft or saggy. The cooling effect was one of the biggest surprises. I tend to sleep hot and usually wake up sweating during the night, but the bamboo-derived fabric feels breathable and much cooler than regular mattress pads I’ve owned before. It stays comfortable throughout the night and doesn’t trap heat like memory foam toppers sometimes do. I also really appreciate the waterproof protection. It gives peace of mind without feeling stiff or making that annoying crinkling noise some waterproof covers have. The surface still feels soft, plush, and smooth. It honestly feels more like a hotel-style pillow top than a basic mattress pad. The thickness is just right for pressure relief. It helped reduce the soreness I usually wake up with in my back, and I’ve been sleeping much more comfortably overall. The deep pockets also held securely on my twin mattress and didn’t slide around, even after moving a lot during sleep. Another thing I liked was how fluffy and well-made it looked right out of the package. After letting it expand for a bit, it became nicely plush and evenly padded. The stitching seems durable, and it still looks great after washing. If you’re looking for a softer, cooler sleeping surface with added waterproof protection and better support for aches and pains, this mattress topper is definitely worth it. It made my bed feel newer and far more comfortable without needing to buy a whole new mattress.
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Reviewed in the United States on May 14, 2026

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